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(NewsTarget) The growing impact of AIDS in Africa, Asia and Latin America has prompted the United Nations World Food Program to appeal to donor countries to fund food and nutrition for those afflicted.

At the XVI International AIDS Conference in Toronto, Robin Jackson, chief of the World Food Program (WFP) HIV/AIDS Service, said, "It is time to deliver more than drugs."

Although those with HIV/AIDS often list food as one of their most desperate needs, nutritional support for HIV programs is usually not touched upon during international HIV policy debates, Jackson said, which leaves the programs seriously under-funded.

"The prioritizing of AIDS drugs over basic nutrition has been a grievous distortion that deprives AIDS victims of what they need most," says Mike Adams, a holistic nutritionist. "What good are drugs when a person is suffering multiple nutritional deficiencies that suppress immune function in the first place? These people need real nutrition, not false hope from patented synthetic chemicals."

Estimates by the WFP state that roughly 1 million of the 6.4 million people expected to enroll in 2008 antiretroviral programs will need nutritional support at a cost of approximately 65 cents a day per patient. Jackson said that when AIDS develops, nutrition and food security become important partners in treatment.

Currently, HIV patients are usually only given rations for 6 months until they can get back on their feet, but Jackson cited a recent study found that malnourished patients exposed to antiretroviral therapy are six times more likely to die than well-nourished patients; possibly because malnutrition impairs people's ability to absorb the triple-drug therapy and renders them unable to benefit from it.

Poor nutrition may also heighten susceptibility to HIV-related diseases, and an undependable food supply can increase the likelihood of individuals adopting lifestyles that often lead to infection.

Tests for HIV have become cheaper and more obtainable for governments, but this has unfortunately lead to standalone HIV testing programs that the Human Rights Watch has criticized for being coercive, discriminatory, lacking in confidentiality and deficient in prevention information.

These programs -- such as the proposal before government in Punjab, India that would require people to get tested to receive or keep a driver's license -- criminalize HIV transmission, are often applied in an arbitrary manner and are impotent to slow the spread of HIV, the Human Rights Watch said.

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A newly redesigned antioxidant may play a critical role in preventing HIV-1-associated dementia, says a University of Missouri-Rolla chemist. Her research will be published in an upcoming issue of the journal Experimental Neurology.

“A third of the adults and half of the children with AIDS develop HIV-1-associated dementia,” explains Dr. Nuran Ercal, professor of chemistry at UMR and adjunct associate professor of internal medicine at Saint Louis University. “Cognitive impairment, postural disorders and tremors are among the most common symptoms encountered in patients suffering from AIDS dementia complex.”

Ercal collaborated with Dr. William Banks, professor of geriatric medicine at Saint Louis University, to determine whether the antioxidant N-acetylcysteine amide (NACA) could prevent cell death and reverse oxidative stress, a condition associated with many different irreversible neurological degeneration diseases, including Parkinson’s and Alzheimer’s.

“There’s a beautiful balance in our bodies,” Ercal says. “We have these free radicals -- atoms and molecules with an unpaired electron that attack other molecules. Our bodies have developed a natural antioxidant defense system that includes enzymes and small molecules to overcome harmful effects of these attacks. If the balance is tipped over, then we have oxidative stress.”

The researchers narrowed their study to the blood-brain barrier, a selective barrier that controls the entry of substances from the blood into the brain. They believed two toxic HIV proteins -- the envelope glycoprotein (gp120) and transregulatory protein (Tat) -- could be disrupting the protective barrier and allowing toxic materials to pass through to the brain. If true, the proteins could be inducing oxidative stress in the cells and causing dementia in patients.

Using an artificial model of a rat’s blood-brain barrier, the researchers incubated cells with the viral proteins for 24 hours. Every parameter the researchers then employed to measure oxidative stress described the same scenario: both gp120 and Tat were inducing oxidative stress in the rat brain capillaries.

In previous studies involving lead poisoning and radiation exposure, Ercal had successfully used the originally formulated N-acetylcysteine (NAC), the drug of choice in treating acetaminophen overdoses, to combat the resulting oxidative stress. Unlike NAC, the newly synthesized NACA passes easily through cell membranes, leading researchers to believe NACA could reverse the oxidative stress levels in the blood-brain barrier.

“We found NACA, this new compound, prevented cell death,” Ercal adds. “NACA returned all parameters to their control levels, and it’s not harmful except in extremely high concentrations. Therefore, we determined that while treating AIDS patients, perhaps we should include antioxidants to prevent oxidative stress or prevent possible dementia.”

The researchers are now studying the brain and liver samples from transgenic rats. The animals have been genetically modified to contain gp120, allowing the researchers to further study the effects of this protein.

“If gp120 is causing these free radicals, then we should have lots of free radicals in these animals because they are continuously making this protein,” Ercal adds

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(NewsTarget) A recent survey of 2,000 HIV and AIDS patients in Britain found that 69 percent were concerned with the long-term toxic side effects of HIV medications.

The survey, conducted by the UK Coalition of People Living with HIV and AIDS, also found that HIV patients were concerned about short-term drug side effects as well as the negative interactions of HIV drugs with other medications.

Edinburgh resident Nikk Bowden, who has been infected with AIDS for seven years, says he is concerned about what long-term use of HIV drugs could do to his body: "If you are expected to be on them for 30 to 40 years, as some doctors will tell you, what is going to happen further down the line?"

Bowden questions whether or not research on long-term side effects of the drugs is ongoing, or has been conducted at all. "It is a worry that you could be taking something that isn't fully understood over a period of time," Bowden says.

HIV drug side effects can include muscle pain and muscle wasting, pancreas and liver problems, nerve damage, fat redistribution and diabetes. Today, 40 million people worldwide are living with HIV/AIDS, and at the end of 2005, 1.3 million HIV-positive residents of poor countries had access to HIV drugs.

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The crimes committed against children define some of the Holocaust's most morally despicable horrors. In It's My Story, Palmer told Handscomb of the abuses she received as a 13-year-old at Auschwitz. As a result of the damage done to her body by the contraceptive drug experiments forced upon her at Auschwitz, she had to undergo several painful surgeries immediately following the war and, even after the surgeries, Palmer remained unable to bear children for the rest of her life. Today, in her 70s, Palmer has cancer.

Now, no one can say for certain whether or not Palmer's cancer is linked to the medical experiments she underwent roughly 60 years earlier, but it is a likely possibility. Exposure to drugs and other chemicals produces extremely negative effects on children, especially those who are even younger than Palmer was during the experiments.

In the April 2004 Pediatrics article "Trends in Environmentally Related Childhood Diseases," Tracey Woodruff, et al. writes, "Children may be particularly susceptible to exposures in utero or during early life because the fetus' or young child’s physiology is undergoing rapid development, such as rapid cell division, changing metabolic activity, and evolving hormonal systems."

With this in mind, running experimental drug studies on children seems especially dangerous and thus horrendous, yet it is still a common occurrence even in modern society. In her Nov. 30, 2004 BBC News article "Guinea Pig Kids" and her subsequent documentary of the same name, Jamie Doran reveals New York City's Administration for Children's Services' (ACS) little-known practice of using HIV-positive children kept in the city's orphanages and foster care homes as human guinea pigs for experimental AIDS drugs. For his documentary and article, Doran interviewed Jacklyn Hoerger, a pediatric nurse who worked at the Catholic Church-run Incarnation Children's Home in Harlem. Hoerger maintains that social work authorities never told her that the drugs she and the other Incarnation employees were administering the orphans and foster care children were experimental. "We were told that if they were vomiting, if they lost their ability to walk, if they were having diarrhea, if they were dying, then all of this was because of their HIV infection," she said to BBC.

In reality, these symptoms were due to the experimental drugs that the workers were giving them. When BBC asked him his opinion on the experimental drug studies done on New York City's orphans and foster children, University of Berkeley visiting scholar Dr. David Rasnick explained, "We're talking about serious, serious side effects. These children are going to be absolutely miserable. They're going to have cramps, diarrhea and their joints are going to swell up. They're going to roll around the ground and you can't touch them." According to BBC reporter Doran, Dr. Rasnick went on to call the experimental AIDS drugs that were given to the children "lethal." If children refused to take them by mouth, workers at Incarnation force-fed them the drugs through feeding tubes inserted into their stomachs.

It's no doubt that these HIV-positive and AIDS symptomatic children needed medication. The question is why were they given experimental drugs, rather than the same medications that a child living in an expensive brownstone on the Upper East Side would have received? In the words of Alliance for Human Research Protection spokesperson Vera Sherav: "They tested these highly experimental drugs. Why didn't they provide the children with the current best treatment? That's the question we have. Why did they expose them to risk and pain, when they were helpless? Would they have done those experiments with their own children? I doubt it." Furthermore -- when you consider the fact that, according to the BBC article, 99 percent of the children in New York City children's homes are either African American or Hispanic -- issues of race and prejudice also come into play.

Hoerger told BBC that she didn't realize what was going on until she later took two children from Incarnation home as foster children. As a trained pediatric nurse, she decided to take the two children she was caring for in her home off the medications given to them while at Incarnation. This resulted in "an immediate boost to their health and happiness," according to BBC. However, soon after her decision, ACS came to her home and took the children out of her care. She was then labeled a child abuser in court and, after that, she never saw the children again.

Performing medical experiments on children is a serious accusation. Realizing this, while working on his documentary and article, Doran went to Incarnation for its side of the story, but it only referred him to its public relations firm. The expensive Manhattan firm told him that it didn't give comments about what goes on inside the home. In light of these accusations, former ACS Commissioner John B. Mattingly ordered a comprehensive review of all ACS records. By early April, based on the records they had examined, ACS staff members revealed just how common the experimentation Hoerger described at Incarnation was throughout the city:

• Between 1988 and 2001, 465 foster care children and orphans were used in experimental AIDS drug trials.
• Most of these children participated before 1996.
• The majority of HIV-positive children living in New York City were diagnosed from the mid-1980s through the mid-1990s.
• The highest number of AIDS-related deaths among New York City children happened from 1990 to 1995.
• The 465 children used in the studies were in approximately two dozen different independent agencies operating under contract to ACS.

Then, on Apr. 22, 2005, ACS sent out a press release stating that it had "contracted with the Vera Institute of Justice to conduct an independent review of ACS policy and practice regarding the enrollment of HIV-positive children in foster care in clinical drug trials during the late 1980s and 1990s." It also asserted: "The last child to enter an HIV-related clinical trial while in foster care did so in 2001. There are no ongoing HIV-related clinical trials involving children in foster care in New York City." This directly contradicts the conclusion Doran writes in his 2004 article: "The experiments continue to be carried out on the poor children of New York City."

ACS maintains that it ordered the studies with the best interest of HIV-positive children in mind. "The purpose of the drug trials was to develop effective treatments for pediatric AIDS, at a time when there were no known, FDA-approved medications available to treat children with the disease, and many children were dying," reads the press release. As proof of the gravity of the AIDS crisis ACS faced when conducting the trials, the press release cites the following figures from the New York City Department of Health and Mental Hygiene:

• Out of the 13,927 HIV-positive children under age 13 nationwide prior to 2003 (according to CDC estimates), the percentage of HIV-positive children in New York City was "the highest by far of any jurisdiction in the country."
• From 1979 through 2003, 3,634 children living in New York City and under the age of 13 were HIV positive.

Even though ACS believes that its decision to give the experimental AIDS drugs to the 465 foster children and orphans was not wrong, it is nevertheless ordering the Vera Institute to conduct the independent study, so as to assure the public and the media. As Commissioner Mattingly explained, "We are taking this step because, while we believe that the policies in place at the time reflected good practice, we acknowledge the need for transparency in all of our dealings with the public. In order for us to be effective in our mission to protect New York City’s children, we must have a sense of mutual trust with those families we seek to serve." According to the press release, the Vera Institute "will research ACS policies and procedures to ensure that HIV-positive children and children with AIDS who were in the care of ACS were appropriately enrolled in the correct clinical drug trials." This includes finding out whether:

• ACS obtained consent from the children's parents or other guardians before enrolling them in the experimental drug studies.
• The children enrolled in the trials met the medical criteria to do so.
• ACS adequately and properly monitored the children who were enrolled.
• Enrollment was "appropriate based on sound medical knowledge at the time."

As of an Oct. 5, 2005 update to its web site regarding the analysis, the Vera Institute still had not completed its investigation. It writes that it is "assembling an advisory board of medical, child welfare, legal, and community experts to review our findings and assure the public of the independence of our research." Meanwhile, in its description of the project, the Vera Institute acknowledges both sides of the controversy:

"Opponents of involving foster children in clinical trials -- where the risks and benefits are often unknown -- worry that this highly vulnerable population may be too-easily neglected or even exploited. When it comes to children of color, in particular, they point to historic examples where the health care system has acted in discriminatory and prejudicial ways.

"On the other hand, those who favor including foster children in clinical trials argue that enrollment can provide high quality care and cutting-edge medicine to children who otherwise would receive only routine medical services. In this view, excluding foster children unfairly bars them from the best the medical profession has to offer."

It will be very interesting to see the Vera Institute's findings -- which are, according to the Institute itself -- "part of Vera's mission to improve government systems." "We hope that the information we provide will contribute to the public debate that will help shape future policies regarding clinical trials and children in government custody," the site reads. On a national level, between 12,000 and 13,000 children under the age of 13 have participated in National Institutes of Health-sponsored AIDS drug trials from 1986 to 2005.

Even though the Vera Institute's findings are not yet complete, the Environmental Protection Agency's (EPA) Apr. 8, 2005 cancellation of its Children's Health Environmental Exposure Research Study (CHEERS) shows what a combination of intense opposition from environmental and public health groups (as well as a little help from Congress) can do to end experimentation on poverty-stricken children.

Child medical experiments at the EPA

In October 2005, the American Chemistry Council gave the EPA $2.1 million to study how children ranging from infancy to three years old ingest, inhale or absorb chemicals. Like IG Farben was for the German pharmaceutical companies of Nazi Germany, the American Chemistry Council acts much like a front group for chemical industry bigwigs like Bayer (which was incidentally also a member of IG Farben), BP, Chevron, Dow, DuPont, Exxon, Honeywell, 3M, Monsanto and Procter & Gamble. Studies have already proven that the chemicals made by these companies have long-term effects on children and adults. A short, two-year study like CHEERS would of course fail to reveal these long-term effects and the American Chemistry Council could then publicize these findings as "proof" that its chemicals were safe.

This represents an ethical problem in itself, but the demographic of the proposed child test subjects worsen the issue, especially in light of the use of foster children (the majority of which were African-American and Hispanic) by both the New York City ACS and the Tuskegee Syphilis Study. According to the EPA's original study proposal, portions of which were reprinted by the Organic Consumers Association, test subjects would be chosen from six health clinics in Duvall County, Fla. Given the characteristics of these health centers, page 23 of the study proposal itself highlights that minority children from low-income families would be the likely test subjects: "Although all Duval County citizens are eligible to use the [health care] centers, they primarily serve individuals with lower incomes. In the year 2000, seventy five percent of the users of the clinics for pregnancy issues were at or below the poverty level ... The percentage of births to individuals classified as black in the U.S. Census is higher at these three hospitals than for the County as a whole."

In fact, the health care centers report that 51 percent of their births are to non-Caucasian mothers, and that 62 percent of mothers received only elementary school or secondary school educations. If the EPA were to have proceeded with CHEERS, children born to these health care centers would have been used as human guinea pigs simply because they belong to minority groups and poverty-stricken families. In return for allowing their children to be exposed to toxic chemicals, the families were to have received $970, a free video camera, a T-shirt and a framed certificate of appreciation.

Fortunately, the EPA decided not to go through with CHEERS, once U.S. Senators Bill Nelson (D-Fla.) and Barbara Boxer (D-Calif.) decided to put their feet down and block President Bush's nomination of Stephen Johnson for head of the EPA. In his Apr. 8 statement, Johnson reversed the EPA's earlier decision to await a report from an independent science advisory panel before making a decision about CHEERS. He explained his decision as being a result of public and media "misrepresentations" of the study:

"Last fall, in light of questions about the study design, I directed that all work on the study stop immediately and requested an independent review. Since that time, many misrepresentations about the study have been made. EPA senior scientists have briefed me on the impact these misrepresentations have had on the ability to proceed with the study.

"I have concluded that the study cannot go forward, regardless of the outcome of the independent review. EPA must conduct quality, credible research in an atmosphere absent of gross misrepresentation and controversy."

Boxer, who says that she will continue to oppose testing toxins on humans, called CHEERS an "immoral program to test pesticides on children" and "a reprehensible idea that never should have made it out of the boardroom" in her statement to the Associated Press following Johnson's decision. Luckily, unlike Tuskegee, the study was stopped before anyone got hurt.

This story continues in part three.

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The CIA continues a limited number of MKULTRA plans by beginning Project MKSEARCH to develop and test ways of using biological, chemical and radioactive materials in intelligence operations, and also to develop and test drugs that are able to produce predictable changes in human behavior and physiology (Goliszek).

Dr. Henry Beecher writes, "The well-being, the health, even the actual or potential life of all human beings, born or unborn, depend upon the continuing experimentation in man. Proceed it must; proceed it will. 'The proper study of mankind is man,'" in his "exposé" on human medical experimentation Research and the Individual ("Human Experimentation: Before the Nazi Era and After").

U.S. Army scientists drop light bulbs filled with Bacillus subtilis through ventilation gates and into the New York City subway system, exposing more than one million civilians to the bacteria (Goliszek).

The National Commission for the Protection of Research Subjects issues its Policies for the Protection of Human Subjects, which eventually creates what we now know as institutional review boards (IRBs) (Sharav).

(1967)

Continuing on his Dow Chemical Company-sponsored dioxin study without the company's knowledge or consent, University of Pennsylvania Professor Albert Kligman increases the dosage of dioxin he applies to 10 prisoners' skin to 7,500 micrograms, 468 times the dosage Dow official Gerald K. Rowe had authorized him to administer. As a result, the prisoners experience acne lesions that develop into inflammatory pustules and papules (Kaye).

The CIA places a chemical in the drinking water supply of the FDA headquarters in Washington, D.C. to see whether it is possible to spike drinking water with LSD and other substances (Cockburn and St. Clair, eds.).

In a study published in the Journal of Clinical Investigation, researchers inject pregnant women with radioactive cortisol to see if the radioactive material will cross the placentas and affect the fetuses (Goliszek).

The U.S. Army pays Professor Kligman to apply skin-blistering chemicals to Holmesburg Prison inmates' faces and backs, so as to, in Professor Kligman's words, "learn how the skin protects itself against chronic assault from toxic chemicals, the so-called hardening process," information which would have both offensive and defensive applications for the U.S. military (Kaye).

The CIA and Edgewood Arsenal Research Laboratories begin an extensive program for developing drugs that can influence human behavior. This program includes Project OFTEN -- which studies the toxicology, transmission and behavioral effects of drugs in animal and human subjects -- and Project CHICKWIT, which gathers European and Asian drug development information (Goliszek).

Professor Kligman develops Retin-A as an acne cream (and eventually a wrinkle cream), turning him into a multi-millionaire (Kaye).

Researchers paralyze 64 prison inmates in California with a neuromuscular compound called succinylcholine, which produces suppressed breathing that feels similar to drowning. When five prisoners refuse to participate in the medical experiment, the prison's special treatment board gives researchers permission to inject the prisoners with the drug against their will (Greger).

(1968)

Planned Parenthood of San Antonio and South Central Texas and the Southwest Foundation for Research and Education begin an oral contraceptive study on 70 poverty-stricken Mexican-American women, giving only half the oral contraceptives they think they are receiving and the other half a placebo. When the results of this study are released a few years later, it stirs tremendous controversy among Mexican-Americans (Sharav, Sauter).

(1969)

President Nixon ends the United States' offensive biowarfare program, including human experimentation done at Fort Detrick. By this time, tens of thousands of civilians and members of the U.S. armed forces have wittingly and unwittingly acted as participants in experiments involving exposure to dangerous biological agents (Goliszek).

The U.S. military conducts DTC Test 69-12, which is an open-air test of VX and sarin nerve agents at the Army's Edgewood Arsenal in Maryland, likely exposing military personnel (Goliszek, Martin).

Experimental drugs are tested on mentally disabled children in Milledgeville, Ga., without any institutional approval whatsoever (Sharav).

Dr. Donald MacArthur, the U.S. Department of Defense's Deputy Director for Research and Technology, requests $10 million from Congress to develop a synthetic biological agent that would be resistant "to the immunological and therapeutic processes upon which we depend to maintain our relative freedom from infectious disease" (Cockburn and St. Clair, eds.).

Judge Sam Steinfield's dissent in Strunk v. Strunk, 445 S.W.2d 145 marks the first time a judge has ever suggested that the Nuremberg Code be applied in American court cases (Sharav).

(1970)

A year after his request, under H.R. 15090, Dr. MacArthur receives funding to begin CIA-supervised mycoplasma research with Fort Detrick's Special Operations Division and hopefully create a synthetic immunosuppressive agent. Some experts believe that this research may have inadvertently created HIV, the virus that causes AIDS (Goliszek).

Under order from the National Institutes of Health (NIH), which also sponsored the Tuskegee Experiment, the free childcare program at Johns Hopkins University collects blood samples from 7,000 African-American youth, telling their parents that they are checking for anemia but actually checking for an extra Y chromosome (XYY), believed to be a biological predisposition to crime. The program director, Digamber Borganokar, does this experiment without Johns Hopkins University's permission (Greger, Merritte, et al.).

(1971)

President Nixon converts Fort Detrick from an offensive biowarfare lab to the Frederick Cancer Research and Development Center, now known as the National Cancer Institute at Frederick. In addition to cancer research, scientists study virology, immunology and retrovirology (including HIV) there. Additionally, the site is home to the U.S. Army Medical Research Institute, which researches drugs, vaccines and countermeasures for biological warfare, so the former Fort Detrick does not move far away from its biowarfare past (Goliszek).

Stanford University conducts the Stanford Prison Experiment on a group of college students in order to learn the psychology of prison life. Some students are given the role as prison guards, while the others are given the role of prisoners. After only six days, the proposed two-week study has to end because of its psychological effects on the participants. The "guards" had begun to act sadistic, while the "prisoners" started to show signs of depression and severe psychological stress (University of New Hampshire).

An article entitled "Viral Infections in Man Associated with Acquired Immunological Deficiency States" appears in Federation Proceedings. Dr. MacArthur and Fort Detrick's Special Operations Division have, at this point, been conducting mycoplasma research to create a synthetic immunosuppressive agent for about one year, again suggesting that this research may have produced HIV (Goliszek).

(1972)

In studies sponsored by the U.S. Air Force, Dr. Amedeo Marrazzi gives LSD to mental patients at the University of Missouri Institute of Psychiatry and the University of Minnesota Hospital to study "ego strength" (Barker).

(1973)

An Ad Hoc Advisory Panel issues its Final Report on the Tuskegee Syphilis Study, writing, "Society can no longer afford to leave the balancing of individual rights against scientific progress to the scientific community" (Sharav).

(1974)

Congress enacts the National Research Act, creating the National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research and finally setting standards for human experimentation on children (Breslow).

(1975)

The Department of Health, Education and Welfare gives the National Institutes of Health's Policies for the Protection of Human Subjects (1966) regulatory status. Title 45, known as "The Common Rule," officially creates institutional review boards (IRBs) (Sharav).

(1977)

The Kennedy Hearing initiates the process toward Executive Order 12333, prohibiting intelligence agencies from experimenting on humans without informed consent (Merritte, et al.).

The U.S. government issues an official apology and $400,000 to Jeanne Connell, the sole survivor from Col. Warren's now-infamous plutonium injections at Strong Memorial Hospital, and the families of the other human test subjects (Burton Report).

The National Urban League holds its National Conference on Human Experimentation, stating, "We don't want to kill science but we don't want science to kill, mangle and abuse us" (Sharav).

(1978)

The CDC begins experimental hepatitis B vaccine trials in New York. Its ads for research subjects specifically ask for promiscuous homosexual men. Professor Wolf Szmuness of the Columbia University School of Public Health had made the vaccine's infective serum from the pooled blood serum of hepatitis-infected homosexuals and then developed it in chimpanzees, the only animal susceptible to hepatitis B, leading to the theory that HIV originated in chimpanzees before being transferred over to humans via this vaccine. A few months after 1,083 homosexual men receive the vaccine, New York physicians begin noticing cases of Kaposi's sarcoma, Mycoplasma penetrans and a new strain of herpes virus among New York's homosexual community -- diseases not usually seen among young, American men, but that would later be known as common opportunistic diseases associated with AIDS (Goliszek).

(1979)

The National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research releases the Belmont Report, which establishes the foundations for research experimentation on humans. The Belmont Report mandates that researchers follow three basic principles: 1. Respect the subjects as autonomous persons and protect those with limited ability for independence (such as children), 2. Do no harm, 3. Choose test subjects justly -- being sure not to target certain groups because of they are easily accessible or easily manipulated, rather than for reasons directly related to the tests (Berdon).

(1980)

A study reveals a high incidence of leukemia among the 18,000 military personnel who participated in 1957's Operation Plumbbob (a href="http://en.wikipedia.org/wiki/Operation_Plumbbob">"Operation Plumbob").

According to blood samples tested years later for HIV, 20 percent of all New York homosexual men who participated in the 1978 hepatitis B vaccine experiment are HIV-positive by this point (Goliszek).

American http://www.newstarget.com/doctors.html>doctors give experimental hormone shots to hundreds of Haitian men confined to detention camps in Miami and Puerto Rico, causing the men to develop a condition known as gynecomastia, in which men develop full-sized breasts (Cockburn and St. Clair, eds.).

The CDC continues its 1978 hepatitis B vaccine experiment in Los Angeles, San Francisco, Chicago, St. Louis and Denver, recruiting over 7,000 homosexual men in San Francisco alone (Goliszek).

The FDA prohibits the use of prison inmates in pharmaceutical drug trials, leading to the advent of the experimental drug testing centers industry (Sharav).

The first AIDS case appears in San Francisco (Goliszek).

(1981)

(1981 - 1993) The Seattle-based Genetic Systems Corporation begins an ongoing medical experiment called Protocol No. 126, in which cancer patients at the Fred Hutchinson Cancer Research Center in Seattle are given bone marrow transplants that contain eight experimental proteins made by Genetic Systems, rather than standard bone marrow transplants; 19 human subjects die from complications directly related to the experimental treatment (Goliszek).

A deep diving experiment at Duke University causes test subject Leonard Whitlock to suffer permanent brain damage (Sharav).

The CDC acknowledges that a disease known as AIDS exists and confirms 26 cases of the disease -- all in previously healthy homosexuals living in New York, San Francisco and Los Angeles -- again supporting the speculation that AIDS originated from the hepatitis B experiments from 1978 and 1980 (Goliszek).

(1982)

Thirty percent of the test subjects used in the CDC's hepatitis B vaccine experiment are HIV-positive by this point (Goliszek).

(1984)

SFBC Phase I research clinic founded in Miami, Fla. By 2005, it would become the largest experimental drug testing center in North America with centers in Miami and Montreal, running Phase I to Phase IV clinical trials (Drug Development-Technology.com).

(1985)

A former U.S. Army sergeant tries to sue the Army for using drugs on him in without his consent or even his knowledge in United States v. Stanley, 483 U.S. 669. Justice Antonin Scalia writes the decision, clearing the U.S. military from any liability in past, present or future medical experiments without informed consent (Merritte, et al..

(1987)

Philadelphia resident Doris Jackson discovers that researchers have removed her son's brain post mortem for medical study. She later learns that the state of Pennsylvania has a doctrine of "implied consent," meaning that unless a patient signs a document stating otherwise, consent for organ removal is automatically implied (Merritte, et al.).

(1988)

The U.S. Justice Department pays nine Canadian survivors of the CIA and Dr. Cameron's "psychic driving" experiments (1957 - 1964) $750,000 in out-of-court settlements, to avoid any further investigations into MKULTRA (Goliszek).

(1988 - 2001) The New York City Administration for Children's Services begins allowing foster care children living in about two dozen children's homes to be used in National Institutes of Health-sponsored (NIH) experimental AIDS drug trials. These children -- totaling 465 by the program's end -- experience serious side effects, including inability to walk, diarrhea, vomiting, swollen joints and cramps. Children's home employees are unaware that they are giving the HIV-infected children experimental drugs, rather than standard AIDS treatments (New York City ACS, Doran).

(1990)

The United States sends 1.7 million members of the armed forces, 22 percent of whom are African-American, to the Persian Gulf for the Gulf War ("Desert Storm"). More than 400,000 of these soldiers are ordered to take an experimental nerve agent medication called pyridostigmine, which is later believed to be the cause of Gulf War Syndrome -- symptoms ranging from skin disorders, neurological disorders, incontinence, uncontrollable drooling and vision problems -- affecting Gulf War veterans (Goliszek; Merritte, et al.).

The CDC and Kaiser Pharmaceuticals of Southern California inject 1,500 six-month-old black and Hispanic babies in Los Angeles with an "experimental" measles vaccine that had never been licensed for use in the United States. Adding to the risk, children less than a year old may not have an adequate amount of myelin around their nerves, possibly resulting in impaired neural development because of the vaccine. The CDC later admits that parents were never informed that the vaccine being injected into their children was experimental (Goliszek).

The FDA allows the U.S. Department of Defense to waive the Nuremberg Code and use unapproved drugs and vaccines in Operation Desert Shield (Sharav).

(1991)

In the May 27 issue of the Los Angeles Times, former U.S. Navy radio operator Richard Jenkins writes that he suffers from leukemia, chronic fatigue and kidney and liver disease as a result of the radiation exposure he received in 1958's Operation Hardtack (Goliszek).

While participating in a UCLA study that withdraws schizophrenics off of their medications, Tony LaMadrid commits suicide (Sharav).

(1992)

Columbia University's New York State Psychiatric Institute and the Mount Sinai School of Medicine give 100 males -- mostly African-American and Hispanic, all between the ages of six and 10 and all the younger brothers of juvenile delinquents -- 10 milligrams of fenfluramine (fen-fen) per kilogram of body weight in order to test the theory that low serotonin levels are linked to violent or aggressive behavior. Parents of the participants received $125 each, including a $25 Toys 'R' Us gift certificate (Goliszek).

(1993)

Researchers at the West Haven VA in Connecticut give 27 schizophrenics -- 12 inpatients and 15 functioning volunteers -- a chemical called MCPP that significantly increases their psychotic symptoms and, as researchers note, negatively affects the test subjects on a long-term basis ("Testimony of Adil E. Shamoo, Ph.D.").

(1994)

In a double-blind experiment at New York VA Hospital, researchers take 23 schizophrenic inpatients off of their medications for a median of 30 days. They then give 17 of them 0.5 mg/kg amphetamine and six a placebo as a control, following up with PET scans at Brookhaven Laboratories. According to the researchers, the purpose of the experiment was "to specifically evaluate metabolic effects in subjects with varying degrees of amphetamine-induced psychotic exacerbation" ("Testimony of Adil E. Shamoo, Ph.D.").

Albuquerque Tribune reporter Eileen Welsome receives a Pulitzer Prize for her investigative reporting into Col. Warren's plutonium experiments on patients at Strong Memorial Hospital in 1945 (Burton Report).

In a federally funded experiment at New York VA Medical Center, researchers give schizophrenic veterans amphetamine, even though central nervous system stimulants worsen psychotic symptoms in 40 percent of schizophrenics ("Testimony of Adil E. Shamoo, Ph.D.").

Researchers at Bronx VA Medical Center recruit 28 schizophrenic veterans who are functioning in society and give them L-dopa in order to deliberately induce psychotic relapse ("Testimony of Adil E. Shamoo, Ph.D.").

President Clinton appoints the Advisory Commission on Human Radiation Experiments (ACHRE), which finally reveals the horrific experiments conducted during the Cold War era in its ACHRE Report.

(1995)

A 19-year-old University of Rochester student named Nicole Wan dies from participating in an MIT-sponsored experiment that tests airborne pollutant chemicals on humans. The experiment pays $150 to human test subjects (Sharav).

In the Mar. 15 President's Advisory Committee on Human Radiation Experiments (ACHRE), former human subjects, including those who were used in experiments as children, give sworn testimonies stating that they were subjected to radiation experiments and/or brainwashed, hypnotized, drugged, psychologically tortured, threatened and even raped during CIA experiments. These sworn statements include:

• Christina DeNicola's statement that, in Tucson, Ariz., from 1966 to 1976, "Dr. B" performed mind control experiments using drugs, post-hypnotic injection and drama, and irradiation experiments on her neck, throat, chest and uterus. She was only four years old when the experiments started.
• Claudia Mullen's testimony that Dr. Sidney Gottlieb (of MKULTRA fame) used chemicals, radiation, hypnosis, drugs, isolation in tubs of water, sleep deprivation, electric shock, brainwashing and emotional, sexual and verbal abuse as part of mind control experiments that had the ultimate objective of turning her, who was only a child at the time, into the "perfect spy." She tells the advisory committee that researchers justified this abuse by telling her that she was serving her country "in their bold effort to fight Communism."
• Suzanne Starr's statement that "a physician, who was retired from the military, got children from the mountains of Colorado for experiments." She says she was one of those children and that she was the victim of experiments involving environmental deprivation to the point of forced psychosis, spin programming, injections, rape and frequent electroshock and mind control sessions. "I have fought self-destructive programmed messages to kill myself, and I know what a programmed message is, and I don’t act on them," she tells the advisory committee of the experiments' long-lasting effects, even in her adulthood (Goliszek).

President Clinton publicly apologizes to the thousands of people who were victims of MKULTRA and other mind-control experimental programs (Sharav).

In Dr. Daniel P. van Kammen's study, "Behavioral vs. Biochemical Prediction of Clinical Stability Following Haloperidol Withdrawal in Schizophrenia," researchers recruit 88 veterans who are stabilized by their medications enough to make them functional in society, and hospitalize them for eight to 10 weeks. During this time, the researchers stop giving the veterans the medications that are enabling them to live in society, placing them back on a two- to four-week regimen of the standard dose of Haldol. Then, the veterans are "washed-out," given lumbar punctures and put under six-week observation to see who would relapse and suffer symptomatic schizophrenia once again; 50 percent do ("Testimony of Adil E. Shamoo, Ph.D.").

President Clinton appoints the National Bioethics Advisory Committee (Sharav).

Justice Edward Greenfield of the New York State Supreme Court rules that parents do not have the right to volunteer their mentally incapacitated children for non-therapeutic medical research studies and that no mentally incapacitated person whatsoever can be used in a medical experiment without informed consent (Sharav).

(1996)

Professor Adil E. Shamoo of the University of Maryland and the organization Citizens for Responsible Care and Research sends a written testimony on the unethical use of veterans in medical research to the U.S. Senate's Committee on Governmental Affairs, stating: "This type of research is on-going nationwide in medical centers and VA hospitals supported by tens of millions of dollars of taxpayers money. These experiments are high risk and are abusive, causing not only physical and psychic harm to the most vulnerable groups but also degrading our society’s system of basic human values. Probably tens of thousands of patients are being subjected to such experiments" ("Testimony of Adil E. Shamoo, Ph.D.").

The Department of Defense admits that Gulf War soldiers were exposed to chemical agents; however, 33 percent of all military personnel afflicted with Gulf War Syndrome never left the United States during the war, discrediting the popular mainstream belief that these symptoms are a result of exposure to Iraqi chemical weapons (Merritte, et al.).

In a federally funded experiment at West Haven VA in Connecticut, Yale University researchers give schizophrenic veterans amphetamine, even though central nervous system stimulants worsen psychotic symptoms in 40 percent of schizophrenics ("Testimony of Adil E. Shamoo, Ph.D.").

President Clinton issues a formal apology to the subjects of the Tuskegee Syphilis Study and their families (Sharav).

(1997)

In order to expose unethical medical experiments that provoke psychotic relapse in schizophrenic patients, the Boston Globe publishes a four-part series entitled "Doing Harm: Research on the Mentally Ill" (Sharav).

Researchers give 26 veterans at a VA hospital a chemical called Yohimbine to purposely induce post-traumatic stress disorder ("Testimony of Adil E. Shamoo, Ph.D.").

In order to create a "psychosis model," University of Cincinnati researchers give 16 schizophrenic patients at Cincinnati VA amphetamine in order to provoke repeats bouts of psychosis and eventually produce "behavioral sensitization" (Sharav).

National Institutes of Mental Health (NIMH) researchers give schizophrenic veterans amphetamine, even though central nervous system stimulants worsen psychotic symptoms in 40 percent of schizophrenics ("Testimony of Adil E. Shamoo, Ph.D.").

In an experiment sponsored by the U.S. government, researchers withhold medical treatment from HIV-positive African-American pregnant women, giving them a placebo rather than AIDS medication (Sharav).

Researchers give amphetamine to 13 schizophrenic patients in a repetition of the 1994 "amphetamine challenge" at New York VA Hospital. As a result, the patients experience psychosis, delusions and hallucinations. The researchers claim to have informed consent ("Testimony of Adil E. Shamoo, Ph.D.").

On Sept. 18, victims of unethical medical experiments at major U.S. research centers, including the National Institutes of Mental Health (NIMH) testify before the National Bioethics Advisory Committee (Sharav).

(1999)

Adil E. Shamoo, Ph.D. testifies on "The Unethical Use of Human Beings in High-Risk Research Experiments" before the U.S. House of Representatives' House Committee on Veterans' Affairs, alerting the House on the use of American veterans in VA Hospitals as human guinea pigs and calling for national reforms ("Testimony of Adil E. Shamoo, Ph.D.").

Doctors at the University of Pennsylvania inject 18-year-old Jesse Gelsinger with an experimental gene therapy as part of an FDA-approved clinical trial. He dies four days later and his father suspects that he was not fully informed of the experiment's risk (Goliszek)

During a clinical trial investigating the effectiveness of Propulsid for infant acid reflux, nine-month-old Gage Stevens dies at Children's Hospital in Pittsburgh (Sharav).

(2000)

The Department of Defense begins declassifying the records of Project 112, including SHAD, and locating and assisting the veterans who were exposed to live toxins and chemical agents as part of Project 112. Many of them have already died (Goliszek).

President Clinton authorizes the Energy Employees Occupational Illness Compensation Act, which compensates the Department of Energy workers who sacrificed their health to build the United States' nuclear defenses (Sharav).

The U.S. Air Force and rocket maker Lockheed Martin sponsor a Loma Linda University study that pays 100 Californians $1,000 to eat a dose of perchlorate -- a toxic component of rocket fuel that causes cancer, damages the thyroid gland and hinders normal development in children and fetuses -- every day for six months. The dose eaten by the test subjects is 83 times the safe dose of perchlorate set by the State of California, which has perchlorate in some of its drinking water. This Loma Linda study is the first large-scale study to use human subjects to test the harmful effects of a water pollutant and is "inherently unethical," according to Environmental Working Group research director Richard Wiles (Goliszek, Envirnomental Working Group).

(2001)

Healthy 27-year-old Ellen Roche dies in a challenge study at Johns Hopkins University in Maryland (Sharav).

On its website, the FDA admits that its policy to include healthy children in human experiments "has led to an increasing number of proposals for studies of safety and pharmacokinetics, including those in children who do not have the condition for which the drug is intended" (Goliszek).

During a tobacco industry-financed Alzheimer's experiment at Case Western University in Cleveland, Elaine Holden-Able dies after she drinks a glass of orange juice containing a dissolved dietary supplement (Sharav).

Radiologist Scott Scheer of Pennsylvania dies from kidney failure, severe anemia and possibly lupus -- all caused by blood pressure drugs he was taking as part of a five-year clinical trial. After his death, his family sues the Institutional Review Board of Main Line Hospitals, the hospital that oversaw the study, and two doctors. Investigators from the federal Office for Human Research Protections, which is part of the Department of Health and Human Services, later conclude in a Dec. 20, 2002 letter to Scheer's oldest daughter: "Your father apparently was not told about the risk of hydralazine-induced lupus … OHRP found that certain unanticipated problems involving risks to subjects or others were not promptly reported to appropriate institutional officials" (Willen and Evans, "Doctor Who Died in Drug Test Was Betrayed by System He Trusted.")

In Higgins and Grimes v. Kennedy Krieger Institute The Maryland Court of Appeals makes a landmark decision regarding the use of children as test subjects, prohibiting non-therapeutic experimentation on children on the basis of "best interest of the individual child" (Sharav).

(2002)

President George W. Bush signs the Best Pharmaceuticals for Children Act (BPCA), offering pharmaceutical companies six-month exclusivity in exchange for running clinical drug trials on children. This will of course increase the number of children used as human test subjects (Hammer Breslow).

(2003)

Two-year-old Michael Daddio of Delaware dies of congestive heart failure. After his death, his parents learn that doctors had performed an experimental surgery on him when he was five months old, rather than using the established surgical method of repairing his congenital heart defect that the parents had been told would be performed. The established procedure has a 90- to 95-percent success rate, whereas the inventor of the procedure performed on baby Daddio would later be fired from his hospital in 2004 (Willen and Evans, "Parents of Babies Who Died in Delaware Tests Weren't Warned").

(2004)

In his BBC documentary "Guinea Pig Kids" and BBC News article of the same name, reporter Jamie Doran reveals that children involved in the New York City foster care system were unwitting human subjects in experimental AIDS drug trials from 1988 to, in his belief, present times (Doran).

(2005)

In response to the BBC documentary and article "Guinea Pig Kids", the New York City Administration of Children's Services (ACS) sends out an Apr. 22 press release admitting that foster care children were used in experimental AIDS drug trials, but says that the last trial took place in 2001 and thus the trials are not continuing, as BBC reporter Jamie Doran claims. The ACS gives the extent and statistics of the experimental drug trials, based on its own records, and contracts the Vera Institute of Justice to conduct "an independent review of ACS policy and practice regarding the enrollment of HIV-positive children in foster care in clinical drug trials during the late 1980s and 1990s" (New York City ACS).

In exchange for receiving $2 million from the American Chemical Society, the EPA proposes the Children's Health Environmental Exposure Research Study (CHEERS) to learn how children ranging from infancy to three years old ingest, inhale and absorb chemicals by exposing children from a poor, predominantly black area of Duval County, Fla., to these toxins. Due to pressure from activist groups, negative media coverage and two Democratic senators, the EPA eventually decides to drop the study on Apr. 8, 2005 (Organic Consumers Association).

Bloomberg releases a series of reports suggesting that SFBC, the largest experimental drug testing center of its time, exploits immigrant and other low-income test subjects and runs tests with limited credibility due to violations of both the FDA's and SFBC's own testing guidelines (Bloomberg).

Works cited:

Alliance for Human Research Protection. "'Monster Experiment' Taught Orphans to Stutter.". June 11, 2001.

Barker, Allen. "The Cold War Experiments." Mind Control.

Berdon, Victoria. "Codes of Medical and Human Experimentation Ethics." The Least of My Brothers.

Brinker, Wendy. "James Marion Sims: Father Butcher." Seed Show.

Burton Report. "Human Experimentation, Plutonium and Col. Stafford Warren."

Cockburn, Alexander and Jeffrey St. Clair, eds. "Germ War: The U.S. Record." Counter Punch.

"Donald Ewan [sic] Cameron." Wikipedia.

Doran, Jamie. "Guinea Pig Kids." BBC News. 30 Nov. 2004.

Drug Development-Technology.com. "SFBC."

Elliston, Jon. "MKULTRA: CIA Mind Control." Dossier: Paranormal Government.

Environmental Working Group. "U.S.: Lockheed Martin's Tests on Humans." CorpWatch.

Global Security. Chemical Corps. 2005.

Goliszek, Andrew. In the Name of Science. New York: St. Martin's, 2003.

Greger, Michael, M.D. Heart Failure: Diary of a Third Year Medical Student.

Griffiths, Joel and Chris Bryson. "Toxic Secrets: Fluoride and the Atom Bomb." Nexus Magazine 5:3. Apr. - May 1998.

Hammer Breslow, Lauren. "The Best Pharmaceuticals for Children Act of 2002: The Rise of the Voluntary Incentive Structure and Congressional Refusal to Require Pediatric Testing." Harvard Journal of Legislation Vol. 40.

"Human Experimentation: Before the Nazi Era and After." Micah Books.

Kaye, Jonathan. "Retin-A's Wrinkled Past." Mind Control. Orig. pub. Penn History Review Spring 1997.

"Manhattan Project: Oak Ridge." World Socialist Web Site. Oct. 18, 2002.

Meiklejohn, Gordon N., M.D. "Commission on Influenza." Histories of the Commissions. Ed. Theodore E. Woodward, M.D. The Armed Forced Epidemiological Board. 1994.

Merritte, LaTasha, et al.. "The Banality of Evil: Human Medical Experimentation in the United States." The Public Law Online Journal. Spring 1999.

Milgram, Stanley. "Milgram Experiment." Wikipedia. 2006.

New York City Administration of Children's Services. Press release. 22 Apr. 2005.

"Operation Plumbbob." Wikipedia. 2005.

"Operation Whitecoat." Religion and Ethics (Episode no. 708). Oct. 24, 2003.

Organic Consumers Association. "EPA and Chemical Industry to Study the Effects of Known Toxic Chemicals on Children". 12 Apr. 2005.

Pacchioli, David. Subjected to Science. Mar. 1996.

"Placebo Effect." Encyclopedia of Alternative Medicine. 2006.

"Project Paperclip." Wikipedia. 2005.

"Reviews and Notes: History of Medicine: Subjected to Science: Human Experimentation in America before the Second World War." Annals of Internal Medicine 123:2. July 15, 1995.

Sharav, Vera Hassner. "Human Experiments: A Chronology of Human Rsearch." Alliance for Human Research Protection.

Sauter, Daniel. Guide to MS 83 [Planned Parenthood of San Antonio and South Central Texas Records, 1931 - 1999]. University of Texas Library. Apr. 2001.

"Testimony of Adil E. Shamoo, Ph.D." News from the Joint Hearing on Suspension of Medical Research at West Los Angeles and Sepulveda VA Medical Facilities and Informed Consent and Patient Safety in VA Medical Research. 21 Apr. 1999.

University of New Hampshire. "Chronology of Cases Involving Unethical Treatment of Human Subjects." Responsible Conduct of Research.

University of Virginia Health System Health Sciences Library. "Bad Blood: The Tuskegee Syphilis Study." 2004.

U.S. Department of Energy. "Chapter 8: Postwar TBI-Effects Experimentation: Continued Reliance on Sick Patients in Place of Healthy "Normals." Advisory Committee on Human Radiation Experiments (ACHRE) Final Report.

Veterans Health Administration. Project 112/Project SHAD. May 26, 2005.

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What is Critical Illness Life Insurance?

There are several policies on the marketplace that offer coverage for various reasons. Critical Illness Life Insurance offers a coverage for critical ill conditions. If the policyholder is "diagnosed" with any type of illness that is long-term then the policy will payout "tax-free" lump sums of cash to the policyholder.

The Critical Life coverage provides a 'list' of diseases, including incurable illnesses that the insurance policy will defend. In addition, if the policyholder fall victim to an accident or incident, the policy will cover the holder, if he is enduringly out of work. Most insurance policies will not cover holders that are suffering prior to taking out the policies. Likewise, if you are undergoing life-long illnesses or disease when you apply for Critical Illness Policies, you won't be allowed to use the coverage to receive medical treatment. If you are having difficulty searching for Critical Illness insurance there are Brokers online that can help you find the coverage you need. The Brokers may find you coverage although you are currently suffering, however your premiums will probably be steep, but the coverage may be adequate.

Currently, the government is in the process of raising the age for retirement disability to "67.' Out of the billions of people in the world, "1 in 5" males has been diagnosed with some form of Critical Illness, and '1 in 6" females have been diagnosed with Critical Illnesses. Since the government is making changes, we can never tell if changes will apply to Medicare and Medicaid, therefore getting Critical Illness Coverage and paying a bit higher Premiums may not be a bad idea.

Nowadays, due to chemicals, other types of pollutions and so forth there are thousands, if not millions of people suffer from Critical Ills. Recently, experts have claimed that the common age for ill patients is around "47." Millions around the world everyday make the same fatal mistake. That mistakes is believing that they are singled out to stay healthy for the rest of their lives. Out of the millions, at least a few hundred fall ill everyday.

The statistics claim that "35" percentage of males and '46" percentage of females over the past few years were diagnosed with cancer, while another "78" percent of patients that endured strokes only lived up to a year and then passed on. The cancerous patients lived as long as five live and then passed on. Just recently statistics showed that nearly 41,000 females in the UK alone were establish as having 'breast cancer." This means that over 130 females are at risk of death. The males in UK equaled more than 23, 000 diagnosed with "Lung Cancer" and lead to nearly 100 males dying. As you can see, Critical Ill Coverage may be more critical than we realize.

More often than not, a person will need to pay for transportation, medical costs, treatment centers, burial, and in-home medical treatment if they are diagnosed with diseases or terminal illnesses. The funeral arrangements alone nowadays will cost the average individual near "18, 000" if not more. Few funerals cost less for the basics, however, Cremation prices today have increased even.

When the roads are rocky, Critical Illness Policies can provide you a wealth of hope. Critical Illness Coverage, I found to be one of the better insurance plans available on the marketplace. Most Critical Illness Policies will cover any Unremitting, Incurable, or other severe illness, which includes in-home treatment, outgoing patient care, ingoing care, and so forth. Furthermore, we can never tell when we will fall victim to incidents or accidents, therefore having the coverage now can save you later. To learn more about Critical Illness Policies it pays to go online, since traveling around will only provide you limited resources. Online you can get Quotes and support by qualified Brokers that will help you find the best plans. Furthermore, Critical Illness is often offered when a person or family takes out Life Insurance. Therefore, the policies are often compliments of Life Coverage, and only cost a few dollars more in most instances. The few dollars now can provide you wealth when Critical Ill comes knocking at your door

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Pregnant women plagued by cravings for pickles and ice cream must remember to include plenty of folic acid in their diets. Shown to reduce the risk of miscarriage and birth defects, folic acid – found primarily in leafy green vegetables – is an absolute necessity for any woman who is pregnant or is considering becoming pregnant. In fact, "health officials at the U.S. Centers for Disease Control and Prevention (CDC) now recommend that all women of childbearing age take folic acid (0.4 mg daily) to protect their future newborns from developing a neural tube defect, an anomaly of the spinal cord," writes Burton Goldberg in Alternative Medicine.

However, it's not just expectant moms who could stand to add more leafy greens to their plates. Because it is useful in combating everything from acne and canker sores to osteoporosis and cancer, we could all benefit from adding more folic acid to our diets. Along with pregnant women, elderly individuals and people suffering from depression or nervous system disorders especially stand to gain from the addition of this B vitamin.

Folic acid, the synthetic form of the B vitamin folate, works primarily in the brain and nervous system and is necessary for the synthesis of DNA, the production of red and white blood cells and of norepinephrine and serotonin in the nervous system. Folic acid also aids in the elimination of the amino acid homocysteine from the blood, a breakdown product of animal protein (methionine, actually) that contributes to heart attacks. A lack of folic acid can lead to anemia, insomnia, irritability and far more serious health problems.

Despite its range of health benefits, many Americans are deficient in the vitamin, coming nowhere near the government's recommended daily allowance of 200 micrograms daily. "The average American gets only 61 percent of the old Recommended Dietary Allowance, which is too low anyway," says James Duke, PhD in Anti-Aging Prescriptions. Part of the reason for the shortfall is that more Americans are choosing to eat more animal foods – which are a poor source of folic acid – rather than folic-acid rich plant foods, like dark green vegetables, legumes, root vegetables and whole grains.

Dr. Andrew Weil, in Ask Dr. Weil, recommends the use of supplements to make up for the deficiency. "As many as 90 percent of Americans don't get that protective 400 micrograms in their diet – for example, you'd have to eat two cups of steamed spinach, a cup of boiled lentils, or eight oranges every day. So it's important to take a supplement, especially if you're a woman and considering having children someday." As Dr. Weil suggests, for women who are deficient in this essential vitamin, the health costs can be especially high.

Folic acid is essential for pregnant women. Not only does it protect against cervical cancer, it also aids in healthy prenatal development and can significantly reduce the risk of serious neural tube birth defects and abnormalities that occur in very early fetal development, such as spina bifida. However, experts say most women aren't getting adequate levels of folic acid early enough to offer the best protection against birth defects.

"Very few women of child bearing years are taking folic acid… If a person waits until pregnant, the fetal abnormality is already established. All women of child-bearing age who might become pregnant should be taking 400 mg of folic acid," advises Dr. James Howenstine in A Physicians Guide To Natural Health Products That Work. To make matters even more difficult, women who take birth control pills are especially prone to deficiency in the B vitamin since birth control pills actually produce folic acid deficiency.

Men planning to become fathers need to monitor their folic acid intake as well, as low folic acid levels in males has been linked to low sperm count, and some studies suggest deficiency can also damage DNA carried by the sperm. Such damaged DNA could lead to chromosomal damage in a fetus, according to Bottom Line Yearbook 2004. In other words, both men and women who plan to have children should increase their folic acid intake for the sake of their baby-to-be.

Folic acid promotes good health for the mind and body, from the earliest stages of life to the latest. Men and women over 60 who feel fatigued and depressed may simply be suffering from a folic acid deficiency. In fact, folic acid deficiency has been linked to depression in patients of all ages, and according to Gary Null'sComplete Guide of Natural Healing, "the lower the level of folic acid in the blood, the higher the degree of depression."

Folic acid can also help ward off dementia, according to Patrick Quillin in Beating Cancer With Nutrition, who wrote that experts estimate up to 20 percent of senility in older adults is simply the result of a long-term deficiency of folic acid and vitamin B-12, which can be aided by taking supplements. However, when taking folic acid supplements, it is important to remember that folic acid and vitamin B-12 work most effectively together, so you should make sure you are getting enough vitamin B-12, as well. Vegans often struggle with this balance since their diets are very rich in folic acid but not in B-12.

The meager representation of folic acid in the American diet can be increased if we all just take a little more care in planning our meals. One way to up folic acid consumption is to make sure your diet includes raw foods, since heat from cooking easily destroys folic acid. And remember, sources of folic acid are plentiful – soybeans, spinach, broccoli, cabbage, peanuts, asparagus, citrus fruits, brussels sprouts, avocado, sunflower seeds, orange juice and don't forget those leafy greens – we just have to be willing to integrate these foods into our diets.

And who wouldn't be willing? After all, some added folic acid could go a long way in helping keep your nervous and circulatory systems in check, while also protecting your body from cancer and heart problems, as well as promoting healthy fetal development in babies. Folic acid is something we need at all stage of life, so we owe it to ourselves to get enough.

The experts speak on folic acid

General information on folic acid

A study is available from the Washington Council for Responsible Nutrition that reports women taking Vitamin E over age 50 and folic acid and Zinc during childbearing years would save Medicare 11 billion dollars, and overall reduce birth defects and coronary heart disease hospital expenses of 20 billion dollars per year.
Anti-Aging Manual by Joseph B Marion, page 100

WHAT IS IT? Even though your body needs only comparatively minuscule amounts of folic acid, it is a vital nutrient. Folic acid—along with all the other nutrients, of course—is your guarantee of optimum physical and mental health. Your levels of folic acid are dependent on outside sources; your body does not make it on its own. Furthermore, it needs vitamin C to work properly. It works in partnership with B12 and B6, as well as the other B vitamins. Folic acid is essential to the production of norepinephrine and serotonin, chemical go-betweens of the nervous system.
Complete Guide Health Nutrition by Gary Null, page 284

Folic acid is one of the B vitamins that is crucial for the synthesis of DNA (genetic material) as well as for many other important cell functions. It was discovered in spinach leaves in 1941 and was named "folate," after the Latin word for leaf (folium). The terms folate and folic acid are roughly synonymous. For the sake of simplicity, I will generally use the latter term. Not surprisingly, this vitamin is mainly found in green leafy vegetables. Although folic acid is not an antioxidant, it boosts the antioxidant network and thus has a place in our story.
Antioxidants Against Cancer by Ralph Moss PhD, page 92

WHO NEEDS folic acid? If you are pregnant, elderly, or suffer from any sort of nervous disorder, you may benefit from additional amounts of folic acid in your diet. Pregnant women, for instance, must be wary of folic acid deficiency. Folic acid supplementation has been helpful in preventing abortion and miscarriage. The elderly need additional folic acid, too. If you are over sixty and depressed, withdrawn, and chronically tired, you may be deficient in this vital element. Let's look at the results of a study in which folic acid was added to the diets of elderly individuals: three groups of patients were used, all with varying degrees of circulation problems. The first group, those with the least degree of difficulty, experienced improved vision less than an hour after receiving folic acid. (Among those with circulatory problems, vision is often impaired because of poor circulation to the optical tissues.)
Complete Guide Health Nutrition by Gary Null, page 284

Folic acid: a water-soluble vitamin of the B complex essential for the synthesis of nucleic acids and necessary for making red blood cells (hematopoiesis), so a deficiency of folic acid results in anemia. After absorption, it is successively reduced to dihydro-folic acid and then tetrahydrofolic acid, the parent compound of the derivatives that act as coenzyme carriers of one-carbon groups in various metabolic reactions.
Building Wellness with DMG by Roger V Kendall PhD, page 216

Red blood cells are built with Vitamins B-12, folic acid, and B6.
Anti-Aging Manual by Joseph B Marion, page 100

And remember, folic acid can be destroyed by exposure to heat and strong light.
Complete Guide Health Nutrition by Gary Null, page 286

Recommendations on folic acid

Doctors routinely advise women who are pregnant, or thinking of becoming pregnant, to supplement folic acid (a B vitamin also known as folate) as a means of safeguarding against birth defects such as spinal malformations.
Anti-Aging Prescriptions by James Duke PhD, page 219

It is becoming increasingly obvious that food supplementation is necessary to prevent cancer and other diseases. The prestigious Institute of Medicine (IOM) of the National Academy of Sciences in 1998 called for supplementation with folic acid and vitamin B12.
Antioxidants Against Cancer by Ralph Moss PhD, page 10

If you're concerned that your diet might not provide enough vitamin B6 and folic acid to prevent stroke, Dr. Lieberman suggests taking supplements of both nutrients. Aim for 300 milligrams of B6 and 800 micrograms of folic acid a day Vitamin B6 doses this high, however, should only be taken under medical supervision. Add E for extra protection.
Blended Medicine by Michael Castleman, page 10

Vegetarians owe it to themselves to be extra careful about their diets. As Richard W. Vilter, M.D., of the University of Cincinnati College of Medicine, warns, "Persons who eat absolutely no animal protein (called vegans) or extreme vegetarians have no source of vitamin B12, but much folic acid in their diets." Frequently in such subjects, neurologic abnormalities develop of the posterolateral column degeneration type. This is a situation analogous to a patient with pernicious anemia who is treated inadequately with a mixed vitamin capsule containing folic acid." There is another danger for those who abstain from animal foods, including dairy products: dietary deficiencies don't show up for five to ten years because the body is able to hold some B12 in reserve. Nerve damage may exist without signs of deficiency until it is too late. The result of degeneration of the nervous system and the spinal cord is so irreparable that death may be the result.
Complete Guide Health Nutrition by Gary Null, page 283

Benefits and uses of folic acid

Folic acid is important during the aging process because it provides nourishment for the brain. Folic acid supports the production of energy and the production of blood cells. Supplementing with folic acid may help in the treatment of depression.
Alternative Medicine by Burton Goldberg, page 321

Three to four hundred milligrams of vitamin B5 and 150 mg of B6 should be consumed on a daily basis, while prescriptions of folic acid can serve as natural hormone replacements. Adequate quantities of essential fatty acids should also be consumed because they act as natural hormone supplements, prevent cancer, and can alleviate the symptoms of aging.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 258

Folic acid, the synthetic form of the B vitamin folate, is incredibly important. For one thing, folate is a key regulator of an amino acid called homocysteine, a breakdown product of animal protein. A number of studies have connected high levels of homocysteine in the blood to arterial disease and heart attacks. Folate helps the body eliminate homocysteine from the blood. Recently, Dr. Howard Morrison, an epidemiologist in Ottawa, was able to make a direct connection between folate and heart disease. He looked at folate levels in the blood of 5,056 men who had participated in a nutrition study in the 1970s, and he found that those with low levels of the vitamin were 69 percent more likely to have died from heart problems in the years since. Folate also has been found to prevent neural tube defects (such as spina bifida and anencephaly) in babies, which are caused when this structure fails to form properly. The neural tube is the embryonic tissue that later becomes the brain and spinal cord. Apparently folic acid is essential to its proper development. Earlier this year, the Food and Drug Administration ordered pasta, rice, and flour makers to add folic acid to their foods as protection against birth defects.
Ask Dr Weil by Andrew Weil MD, page 98

Proper nutritional supplementation can significantly improve cardiovascular conditions, as well as prevent them from occurring in the first place. Useful nutrients include beta carotene; vitamins B3 (niacin), Be, B12, C, and E; folic acid; the minerals calcium, chromium, magnesium, potassium, and selenium; the amino acids L-arginine, L-taurine, and L-carnitine; coenzyme Q10; and pycnogenol.
Alternative Medicine by Burton Goldberg, page 771

According to some studies, folic acid has been helpful in relieving depression, even when used in dosages as low as 400 meg. It can also enhance cerebral circulation. One study showed that people with low levels of folic acid were twice as likely as people with adequate levels to have narrowed arteries in their necks. Psychiatric symptoms also appear to be much higher in people, particularly elderly people, who have low folic acid levels. In one study, low folic acid levels increased likelihood of dementia by 300 percent. folic acid is especially effective at breaking down the common chemical homocysteine, which is a neurotoxin. An appropriate daily dosage would be 400 meg, the amount found in many multiple vitamins.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 247

Folic acid: This is another member of the vitamin B family, found in abundance in liver, kidney, mushrooms, spinach, yeast and green leafy vegetables. It has been used for decades to prevent and treat certain forms of anemia. But folic acid also increases the production of white blood cells crucial in the defense against cancer. In the late 1980s, scientists at the University of Alabama Medical Center found that the folic acid in dark leafy vegetables, oranges and liver could act together with vitamin B to prevent injuries to lung tissue and retard the development of cancer among cigarette smokers. These researchers found that smokers whose lung cells were injured had low levels of both folic acid and vitamin B12. Since these nutrients are necessary to synthesize DNA, a deficiency of one or both of these vitamins could make cells more susceptible to the effects of carcinogens. These vitamins also offered protection against birth defects and cancerous changes in cervical cells.
Cancer Therapy by Ralph W Moss PhD, page 42

Floss one to two times daily and then rinse mouth (for one minute) with several mouthfuls of liquid folic acid (0.1% solution) and then swallow. In one study, 60 individuals with gingivitis rinsed for one minute two times daily and had beneficial results. If you cannot find liquid folic acid, buy folic acid crystals in 800 meg capsules, empty two capsules in water and use this to gargle.
Alternative Medicine by Burton Goldberg, page 1055

Lipotropic factors are compounds that promote the transportation and utilization of fats, and help prevent the accumulation of fat in the liver. They include methionine, choline, folic acid, and vitamin B12.
Cancer And Natural Medicine by John Boik, page 140

Folic acid helps against uric acid.
Anti-Aging Manual by Joseph B Marion, page 560

The four B vitamins that are most important for your brain are B12, B6, B3, and folic acid.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 246

The body uses 75-99% of its Calcium, with Phosphorus, Boron, Manganese, Silica, Magnesium, Copper, Zinc, Strontium; Protein; the Vitamins A, B-Complex, B6, folic acid, Vitamin C, Vitamin D, and Vitamin K to form bone tissue and teeth.
Anti-Aging Manual by Joseph B Marion, page 800

The primary nutritional building blocks of both neurotransmitters are the amino acids tyrosine and phenylalanine. To potentiate the action of these amino acids, folic acid, magnesium, and vitamins C and B can be taken.
Brain Longevity by Dharma Singh Khalsa M.D. with Cameron Stauth, page 213

Part of the vitamin B complex, folic acid is necessary for synthesis of nucleic acids and formation of the heme component of hemoglobin in red blood cells.
Britannica Encyclopedia Volume One, page 674

[Folic acid] is especially helpful for patients with a history of breast cancer, cervical dysplasia, and smoking. For smokers, it cuts down on the adverse effects of nicotine on the lungs.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 84

Treatments using folic acid

Folic acid is also used in the treatment of cervical dysplasia, a pre-cancerous condition of the uterus, and for this reason is also given to women who take birth control pills or who are pregnant.
Alternative Medicine by Burton Goldberg, page 410

Nerves on edge? Folic acid can help. The Lancet, Britain's prestigious medical journal, reports, "In the past decade [however] there has been increasing interest in the role of folate [folic acid] in neuronal metabolism, in neuropsychiatric illness, and in antiepileptic and convulsant mechanisms." When a folic acid deficiency occurs, your nervous system suffers, because there is normally such a high folate concentration in your cerebrospinal fluid. In many psychiatric and geriatric patients with mental dysfunctions, deficiency is common. "This is a promising area for future research," The Lancet adds.
Complete Guide Health Nutrition by Gary Null, page 285

Dr. Aesoph adds that chromium aids in stabilizing the erratic blood sugar seen in alcoholic hypoglycemia, while choline and folic acid are also commonly cited as important supplements to assist in the body's recovery from addiction.
Alternative Medicine by Burton Goldberg, page 480

Homocysteinemia: Persons with elevated levels of homocysteine are at risk for arteriosclerosis. This can and should be corrected with adequate amounts of folic acid, B 12, pyridoxine, and trimethylglycine. The only way you can be sure you are getting adequate amount of therapy is to regularly monitor blood levels of homocysteine. Current estimates are that 30 to 40% of arterial disease is related to high levels of homocysteine.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 220

Vitamin B may help for premenstrual or mid-menstrual cycle acne. Coexisting gum problems suggest the need for folic acid.
Alternative Medicine by Burton Goldberg, page 988

[For] pins and needles in the legs, take folic acid and B-12.
Anti-Aging Manual by Joseph B Marion, page 1100

Take 5 grams Vitamin C, 1 gram Calcium. 1/2 gram Magnesium, 100 mg. B-Complex, extra B6, B-12. and folic acid (for severe depression, requires Vitamin C for absorption).
Anti-Aging Manual by Joseph B Marion, page 800

Find relief in folic acid. One study found that women who experienced problems with constipation had low levels of the B vitamin folic acid in their blood. When the women began taking folic acid supplements, all of their symptoms subsided. Try taking up to 5,000 micrograms a day until the condition subsides, advises clinical nutritionist Shari Lieberman, Ph.D. But check with your doctor first, since dosages of folic acid over 1,000 micrograms should only be taken under medical supervision.
Blended Medicine by Michael Castleman, page 11

Herpes may be helped overnight by chewing folic acid with 500 mg. L-Lysine twice daily, and Zinc tablets.
Anti-Aging Manual by Joseph B Marion, page 455

If agitation or hyperactivity is seen, it is recommended that folic acid should be given in the amount of two 800 microgram tablets for each 125 mg of DMG taken.
Building Wellness with DMG by Roger V Kendall PhD, page 116

Disease prevention with folic acid

Folic acid, a B vitamin, is now known to prevent neural tube defects like spina bifida, a serious abnormality of early fetal development. Unfortunately, by the time most women learn they are pregnant, the critical period has already passed. A major source of folic acid is the cooked greens recommended in the program (another is orange juice). If you are contemplating pregnancy or think there is any possibility that you could get pregnant, for insurance take a daily B-complex vitamin supplement providing 400 micrograms of folic acid.
8 Weeks To Optimum Health By Andrew Weil MD, page 222

Women taking 400 mg of folic acid also have a decreased risk of heart attack and protection against Alzheimer's Disease and stroke. After 15 years of 400 mg of folic acid there is a 75% reduction in the number of women who get colon cancer.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 19

According to University of Washington researchers, 13,500 to 50,000 deaths from cardiovascular disease could be prevented every year if everyone took folic acid (the supplement form of folate) every day. All you need is 200 micrograms a day.
Anti-Aging Prescriptions by James Duke PhD, page 145

SPINA BIFIDA. Failure of the spinal bones to close over nerves arising from the lower end of the spinal cord. May cause paralysis of the legs and incontinence. Associated with poverty, bad housing and is more common in Celtic races and among the sikhs. Most common cause is folic acid deficiency. Prevention only. A woman of childbearing age should increase her consumption of food rich in folic acid, such as Brussels sprouts, spinach, green beans, oranges, potatoes, wholemeal bread, yeast extract. New evidence suggests health is determined before birth by a mother's condition during pregnancy. The UK Department of Health advises 400 micrograms (0.4mg) folic acid until the twelfth week of pregnancy.
Bartrams Encyclopedia of Herbal Medicine by Thomas Bartram, page 25

Perhaps as much as 30 percent of all heart disease is directly caused by high homocysteine levels, he says. That's the bad news. The good news is that three B vitamins—folic acid, B6, and B12—can help convert homocysteine to methionine or cystine, thus protecting your heart. Dr. Baum recommends taking 800 to 1,000 micrograms of folic acid, 400 micrograms of vitamin B12, and 50 milligrams of vitamin B6 daily.
Alternative Cures by Bill Gottlieb, page 337

...Other nutrients may be equally critical to the prevention of osteoporosis. "Vitamin K, silicon, boron, folic acid, magnesium, and manganese all play a role in bone building and need to be consumed through diet or supplements," he says. To prevent osteoporosis, you must get sufficient levels and the proper ratio of these bone nutrients.
Alternative Medicine by Burton Goldberg, page 840

Sources of folic acid

Folic acid, a B vitamin found in green leafy vegetables, nuts, and whole grains, can prevent neural tube defects in fetuses.
Alternative Medicine by Burton Goldberg, page 866

Greens are high in vitamins and minerals, including iron and calcium in forms that the body can absorb and use more readily than supplements. For example, they are a major source of folic acid (folate), a B vitamin that regulates protein metabolism and offers significant protection against coronary heart disease. ("Folate" and "foliage" share the same root.)
8 Weeks To Optimum Health By Andrew Weil MD, page 141

Eat at least eight servings of fruits and vegetables each day. These high-fiber, low-fat foods are typically rich in folic acid and other B vitamins, which reduce the risk for heart disease by helping to prevent arterial blood clots.
Bottom Line Yearbook 2002 by Bottom Line Personnel, page 331

The leafy green that Popeye made famous is among the best plant sources of folate. All you need is 200 micrograms a day. You can get more than that from 1/2 cup of spinach (or lentils, pinto beans, lima beans, black-eyed peas, or sunflower seeds) or a cup or two of spinach soup. What a pleasant way to stave off stroke and heart attack! Of course, spinach and beans aren't the only great sources of folate. Others include parsley, cabbage, asparagus, broccoli, brussels sprouts, endive, okra, avocado, peanuts, sunflower seeds, and orange juice.
Anti-Aging Prescriptions by James Duke PhD, page 145

A major source of folic acid is the cooked greens recommended in the program (another is orange juice).
8 Weeks To Optimum Health By Andrew Weil MD, page 222

Beetroot is rich in potassium, folic acid, and the antioxidant glutathione.
Alternative Medicine by Burton Goldberg, page 173

Legumes: Peas and beans, such as kidney, lima, soybean, navy, black, and lentils, are loaded with protein, folic acid, and amino acids.
Alternative Medicine by Burton Goldberg, page 192

Diets rich in folic acid and B vitamins would turn out to have such powerful benefits for the heart that they could outweigh such "sins" as moderate red meat intake. Could the public be blamed for its confusion?
Betrayal Of Trust By Laurie Garrett, page 394

Folic acid—This substance protects against cervical cancer and is necessary for proper synthesis of RNA and DNA. It is found in beets, cabbage, dark leafy vegetables, eggs, dairy products, citrus fruits, and most fish.
Alternative Medicine by Burton Goldberg, page 591

Dietary folate sources include leafy and dark green vegetables, citrus fruits, cereals, beans, poultry, and egg yolks, but free folic acid occurs only in supplements.
Britannica Encyclopedia Volume One, page 674

Folic acid [is] found in whole grains, chickpeas, soybeans, spinach, broccoli, and cabbage)…
Alternative Medicine by Burton Goldberg, page 745

Probiotics help suppress the growth of yeast, improve digestion by increasing the production of some enzymes, produce acids that fight bacteria, and manufacture nutrients such as vitamins K, Bi, B2, B3, B12, and folic acid.
Alternative Medicine by Burton Goldberg, page 908

Foods rich in folic acid include spinach and other dark green leafy vegetables, broccoli, asparagus, and whole wheat.
Blended Medicine by Michael Castleman, page 10

Many women have also long esteemed certain wild mushrooms, which some thought to be special gifts from Mother Earth. As we now know, naturally grown mushrooms (as opposed to commercial mushrooms grown in the dark) contain folic acid, which helps to prevent birth defects. These delicious and abundant choices, which do not have any poisonous look-alikes, can be eaten when they are underripe.
American Indian Healing Arts by E.Barrie Kavasch and Karen Baar, page 146

Folic acid deficiencies

Folic acid may be the most common vitamin deficiency in the world, since more people are choosing animal foods (poor source of folic acid) over plant foods. The name, folic acid, comes from the Latin term "folium", meaning foliage, since dark green leafy vegetables are a rich source of folic acid. Other good sources of folic acid include brewer's yeast, legumes, asparagus, oranges, cabbage, root vegetables and whole grains. Since folic acid is essential for all new cell growth, disturbances in folic acid metabolism are far reaching, including heart disease (due to more homocysteine in the blood), birth defects, immune suppression, cancer, premature senility and a long list of other conditions. Without adequate folate in the diet, cell growth is like a drunk driver heading down the highway—more likely to do some harm than not.
Beating Cancer With Nutrition by Patrick Quillin, page 180

Birth Control Pills: These pills produce folic acid deficiency. Where there is a lack of folic acid, homocysteine blood levels rise and this is associated with osteoporosis.
A Physicians Guide To Natural Health Products That Work By James Howenstine MD, page 130

Men Need folic acid too. Low folic acid levels in men are associated with low sperm count. A recent study has led investigators to hypothesize that low folic acid could also damage the DNA that sperm carry—which could lead to chromosomal damage in a fetus. Self-defense: Eat plenty of folate-rich fruits and vegetables and fortified grain products.
Bottom Line Yearbook 2004 by Bottom Line Personnel, page 334

B12 anemia is often accompanied by folic acid anemia. One of the reasons folic acid is important is that it fosters healthy prenatal development: It aids in the prevention of birth defects, such as those of the neural tube, and is crucial for proper cell production in the growing fetus. Folic acid is easily consumed by heat; hence, diets that consist primarily of cooked foods, with few raw foods included, often result in this type of deficiency. In addition, young children may develop a folic acid deficiency if they are given goat's milk. (Although superior to cow's milk in many ways, goat's milk lacks folic acid.) Teenagers and adults who are vegetarians may also fall victim to this form of anemia if they do not carefully balance their diets. Finally, folic acid anemia can be induced by alcoholism, which completely drains the body of this nutrient, and by the consumption of certain prescription drugs, such as oral contraceptives and anticancer drugs.
Complete Encyclopedia Of Natural Healing by Gary Null PhD, page 32

Experts have estimated that up to 20% of all senility in older adults is merely a long term deficiency of folic acid and vitamin B-12. The RDA of folate is 200 meg for adults and 400 meg for pregnant women, although the Center for Disease Control has recommended that 800 meg of folic acid would prevent most cases of spinal bifida. Without adequate folic acid in the body, there is a buildup of homocysteine in the blood, which probably generates 10% or more of the 1 million cases of heart disease each year in the U.S.
Beating Cancer With Nutrition by Patrick Quillin, page 180

Deficiencies of folic acid and vitamin B12 may cause some cases of recurrent canker sores, says Flora Parsa Stay, D.D.S., a dentist in Oxnard, California. If you have recurrent sores, she recommends taking 400 micrograms of folic acid and 200 micrograms of vitamin B12 daily.
Alternative Cures by Bill Gottlieb, page 142

Persons with AIDS are often deficient in folic acid, selenium, zinc, and iron.
Alternative Medicine by Burton Goldberg, page 497

Deficiencies in vitamins B6, B12, and folic acid can trigger such neurological changes as a drop in alertness and memory ability as well as numbness and tingling in the legs.
BioMarkers by Williams Evans PhD and Irwin H Rosenberg MD, page 250

Reduced levels of certain vitamins, minerals, and amino acids have been tentatively linked with Alzheimer's, including folic acid, niacin (vitamin B3), thiamin (vitamin Bi), vitamins Be, B12, C, D, and E, magnesium, selenium, zinc, and tryptophan.
Alternative Medicine by Burton Goldberg, page 524

The elderly generally are deficient in Calories, Protein, Iron, Vitamins A and C, Calcium, the B-Complex, especially B-12 and folic acid, and that's with 70% of the elderly in institutions where the diets are carefully planned.
Anti-Aging Manual by Joseph B Marion, page 315

Low levels of folic acid, vitamin B12, pyridoxine, iron, and magnesium are some of the most commonly implicated nutritional influences on depression.
Beat Depression with St John's Wort by Steven Bratman, page 103

[Folate] anemia resulting from too little folic acid, needed for red-blood-cell maturation (see erythrocyte). White-cell and platelet levels are also often low. Progressive gastrointestinal problems develop. It may result from poor diet or from malabsorption, cirrhosis of the liver, or anticonvulsant drugs; it may also occur in the last three months of pregnancy and in severe hemolytic anemia (in which red cells break down). The blood profile resembles that of pernicious anemia. Taking folic acid causes rapid improvement; an adequate diet cures cases caused by malnutrition.
Britannica Encyclopedia Volume One, page 674